Dechallenge and Rechallenge in Drug Side Effects: How Doctors Confirm Which Medication Is Causing Harm
Dechallenge and rechallenge are key clinical tools used to determine if a drug caused a side effect. Stopping the drug to see if symptoms improve (dechallenge) and carefully restarting it to confirm the reaction (rechallenge) provide the strongest evidence of causality in pharmacovigilance.
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